l1000.db: SQLite database of LINCS L1000 metadata

<div>LINCS L1000 measures the transcriptional response to perturbation. `l1000.db` is a SQLite database that we use to store LINCS L1000 data. Our database contains several parts of the L1000 resource that have been converted into user-friendly tables. The database also provides information not available from L1000. Namely, we computed the chemical similarities between L1000 compounds and mapped the L1000 compounds to external vocabularies.</div><div><br></div><div>+ The `cells` table contains the L1000 cell lines.</div><div><div>+ The `sigs` table contains the L1000 signatures.</div></div><div>+ The `perts` table contains the L1000 perturbations.</div><div><div>+ The `similarity` table contains chemical similarity scores for all compound pairs.</div></div>+ The `unichem` table contains a mapping of L1000 compounds to external chemical vocabularies.<div><br></div><div>This database does not contain the L1000 expression data, hence we consider it metadata. `l1000.db.bz2` is bzip2 compressed to reduce file size. Decompress before use.</div><div><br></div><div>We rely on this database when computing consensus signatures for perturbations.</div><div><br></div><div>If using this database, please attribute this figshare deposition and the LINCS L1000 project. Also please abide by the data release policy for the [NIH LINCS Program](http://www.lincsproject.org/data/data-release-policy/).</div>