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N-Benzylhydroxylamine Addition to β-Aryl Enoates. Enantioselective Synthesis of β-Aryl-β-amino Acid Precursors

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posted on 2000-09-29, 00:00 authored by Mukund P. Sibi, Mei Liu
Chiral Lewis acid catalyzed N-benzylhydroxylamine addition to pyrrolidinone-derived enoates afforded β-aryl-β-amino acid derivatives in high enantiomeric purity with moderate to very good chemical efficiency.

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    benzylhydroxylamine additionenantiomeric purityPrecursors Chiral Lewis acidchemical efficiencyBenzylhydroxylamine AdditionEnoateArylderivativeenoatearylEnantioselective Synthesis

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