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Yeast strains used in the current study.

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journal contribution
posted on 2021-09-20, 17:41 authored by Salar Ahmad, Valérie Côté, Xue Cheng, Gaëlle Bourriquen, Vasileia Sapountzi, Mohammed Altaf, Jacques Côté

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Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites
PLOS GeneticsPLOS Genetics

Categories

  • Biophysics
  • Biochemistry
  • Physical Sciences not elsewhere classified
  • Cell Biology
  • Genetics
  • Molecular Biology
  • Biological Sciences not elsewhere classified
  • Developmental Biology

Keywords

histone acetylation targetsrepair pathway choicealternative repair mechanismsdiv >< pbudding yeast rad9nej1 inhibits repairhomologous end joiningfavors end resectioncore nhej factorsalso implicates nua4nhej factors yku80homologous endjoining machineryend resectionnhej factorsnhej mutantsvitro </strand breaksstrand annealingresults establishresection phenotypepreviously reportedmimicking mutantgene regulationdirectly implicatedcell cycleantagonistic relationshipalso detect53bp1 ortholog

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