Viability of HeLa and Hep-G2 cells is attenuated after treatment with FINs.

Cells were incubated for 48 h with a 10-step 1:2 dilution series starting with 10 μM brequinar, 40 μM FIN56, 10 μM FINO2, 50 μM iFSP1, 50 μM IKE and 10 μM RSL3. (A) Cell viability data of HeLa and Hep-G2 after FINs treatment. Data is related to untreated control cells (UTC) and shown as mean values +/- SEM of n = 3 biological replicates. (B) Heatmap of calculated IC_25/50 values (via four-parameter logistic expression) of FINs in HeLa and Hep-G2 cell lines; green: low IC_25/50 values, red high IC_25/50 values.

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