Two new sesquiterpenoids from the marine-sediment-derived fungus Trichoderma harzianum P1-4

Fang, Sheng-Tao; Wang, Ying-Jie; Ma, Xin-Yue; Yin, Xiu-Li; Ji, Nai-Yun

doi:10.6084/m9.figshare.7301930.v1

Two new sesquiterpenoids from the marine-sediment-derived fungus Trichoderma harzianum P1-4

journal contribution

posted on 2018-11-06, 14:15 authored by Sheng-Tao Fang, Ying-Jie Wang, Xin-Yue Ma, Xiu-Li Yin, Nai-Yun Ji

Three cyclonerane sesquiterpenoids, including the known cyclonerodiol (1), together with its new derivatives, (10E)-12-acetoxy-10-cycloneren-3,7 -diol (2) and 12-acetoxycycloneran-3,7-diol (3) were isolated from the cultures of marine-sediment-derived fungus Trichoderma harzianum P1-4. The structures of the new compounds (2 and 3) were elucidated based on extensive spectroscopic methods (1D/2D NMR and HR-MS) and optical rotation analysis.

Funding

Financial support from the Natural Science Foundation for Distinguished Young Scholars of Shandong Province (JQ201712), National Natural Science Foundation of China (31670355), Key Cutting-Edge Research Program of the Chinese Academy of Sciences (QYZDB-SSW-DQC013) is gratefully acknowledged.

Two new sesquiterpenoids from the marine-sediment-derived fungus Trichoderma harzianum P1-4

Funding

Financial support from the Natural Science Foundation for Distinguished Young Scholars of Shandong Province (JQ201712), National Natural Science Foundation of China (31670355), Key Cutting-Edge Research Program of the Chinese Academy of Sciences (QYZDB-SSW-DQC013) is gratefully acknowledged.

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