ol400184t_si_001.pdf (4.32 MB)
Trifluoromethylation of Allylsilanes under Photoredox Catalysis
journal contributionposted on 2013-03-15, 00:00 authored by Satoshi Mizuta, Keary M. Engle, Stefan Verhoog, Oscar Galicia-López, Miriam O’Duill, Maurice Médebielle, Katherine Wheelhouse, Gerasimos Rassias, Amber L. Thompson, Véronique Gouverneur
A new catalytic method to access allylic secondary CF3 products is described. These reactions use the visible light excited Ru(bpy)3Cl2·6H2O catalyst and the Togni or Umemoto reagent as the CF3 source. The photoredox catalytic manifold delivers enantioenriched allylic trifluoromethylated products not accessible under Cu(I) catalysis.