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Three undescribed monoterpene rhamnosides from the aerial parts of Vangueria agrestis

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journal contribution
posted on 25.02.2020, 07:10 by Ahmed G. Osman, Omer Fantoukh, Zulfiqar Ali, Vijayasankar Raman, Mohamed A. Ibrahim, Ikhlas A. Khan

Phytochemical investigation of the methanolic extract of Vangueria agrestis aerial parts led to the isolation and characterization of four monoterpene rhamnosides, two ursane saponins, and six flavonoid glycosides. Of these constituents, are three undescribed monoterpene glycosides, vangagrestosides A-C. The reported constituents comprise the monoterpene glycoside [(2E,6Z)−2,6-dimethyl-8-[O-α-L-rhamnopyranosyl-(1→3)-α-L-rhamnopyranosyl)-oxy]-octadien-1-yl α-L-rhamnopyranoside], the saponins [3-O-[α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl]pomolic acid, and 3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl]pomolic acid], and the flavonoids [narcissoside, rutin, hyperoside, guajavarin, biorobin, and nicotifloroside].


This research is supported by the “Science-Based Authentication of Botanical Ingredients” funded by the Center for Food Safety and Applied Nutrition, US Food and Drug Administration grant number 5U01FD004246. FDA disclaimer: The findings and conclusions in this report are those of the authors only and do not represent FDA positions or policies. Thanks to Dr. Avula for acquiring the mass.