ja051826+_si_001.pdf (1.89 MB)
Download file

The gem-Dialkyl Effect in Electron Transfer Reactions:  Rapid Synthesis of Seven-Membered Rings through an Electrochemical Annulation

Download (1.89 MB)
journal contribution
posted on 08.06.2005, 00:00 by Jeffrey B. Sperry, Dennis L. Wright
An electrochemical furan annulation strategy has been developed for the synthesis of seven-membered rings. Key to the success of the annulation is the placement of a gem-dialkyl group in the tether. Voltammetric studies indicate that this effect lowers the oxidation potential by approximately 110 mV.