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The Microbiome and Cancer Unveiling the Microbe-Tumor Crosstalk

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posted on 2024-08-27, 05:11 authored by Lamlom Taie Lamlom TahawyLamlom Taie Lamlom Tahawy

With more and more evidence showing that gut microbiota significantly affects tumour biology, the complex relationship between

the human microbiome and cancer has attracted a lot of attention. The aim of this study is to introduce an innovative theoretical

framework that integrates information from microbiology, immunology, oncology, and bioinformatics in order to enhance our understanding of the interactions between microorganisms and tumours. The introduction provides a thorough summary of the human

microbiome while highlighting the important role it plays in the development of pathogenic disorders. Moreover, it offers a succinct

overview of key concepts in cancer biology, emphasising the significance of examining the relationship between the microbiome

and illnesses associated with cancer. An exhaustive literature analysis compiles the foremost discoveries about the impact of the

microbiome on cancer. It provides an explanation of how mechanisms such as metabolic relationships, immunological regulation,

and inflammatory pathways function. Lastly, it highlights the deficiencies in existing research that necessitate the implementation

of more comprehensive methods. The results show that the gut microbiota may affect the growth of tumours in certain ways, such

as by changing the immune system, signalling pathways, and bacterial products. Methodological approaches encompass a thorough

examination of existing literature, the integration of fundamental ideas, and the creation of a comprehensive model that visually

represents these intricate relationships. We evaluate the framework's accuracy by generating predicted scenarios and analyzing

the possible consequences for clinical practice and research. We propose new diagnostic indicators and therapeutic techniques that

specifically target the microbiome

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