jo0495079_si_001.pdf (4.82 MB)
Download file

The MPEG Effect:  Improving Asymmetric Processes by Simple Additives

Download (4.82 MB)
journal contribution
posted on 28.05.2004, 00:00 by Jens Rudolph, Nina Hermanns, Carsten Bolm
Small amounts of simple methoxy poly(ethylene glycol)s (MPEGs) have a beneficial effect on catalyzed asymmetric aryl and alkyl transfer reactions onto aldehydes. The enantiomeric excesses of the products are improved, and this “MPEG effect” allows a reduction of the catalyst loading by a factor of 10.