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Synthesis of Oxime-Linked Mucin Mimics Containing the Tumor-Related TN and Sialyl TN Antigens

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journal contribution
posted on 13.10.2001, 00:00 by Lisa A. Marcaurelle, Youngsook Shin, Scarlett Goon, Carolyn R. Bertozzi
The synthesis of oxime-linked mucin mimics was accomplished via the incorporation of multiple ketone residues into a peptide followed by reaction with aminooxy sugars corresponding to the tumor-related TN and sialyl TN (STN) antigens.