ol050617r_si_001.pdf (289.76 kB)
Download file

Synthesis of Nucleoside α-Thiotriphosphates via an Oxathiaphospholane Approach

Download (289.76 kB)
journal contribution
posted on 26.05.2005, 00:00 by Konrad Misiura, Daria Szymanowicz, Wojciech J. Stec
Nucleoside 5‘-O-(α-thiotriphosphates) were obtained in reactions of the appropriate nucleoside 5‘-O-(2-thio-1,3,2-oxathiaphospholanes) with pyrophosphate in the presence of DBU. The presented method allows also for preparation of α-seleno congeners and corresponding α-modified diphosphates.

History