figshareBrowse
ppat.1009718.s014.docx (31.37 kB)
Download file

Supplemental Materials and Methods.

Download (31.37 kB)
journal contribution
posted on 24.01.2022, 18:39 by Nawar Naseer, Marisa S. Egan, Valeria M. Reyes Ruiz, William P. Scott, Emma N. Hunter, Tabitha Demissie, Isabella Rauch, Igor E. Brodsky, Sunny Shin

(DOCX)

History

Usage metrics

Read the peer-reviewed publication

Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication
PLOS PathogensPLOS Pathogens

Categories

Keywords

deliver virulence factorscytosolic immune sensorst3sss ), termeddetecting t3ss ligandsinvade host cells1 t3ss needle1 t3ss enablessalmonella enterica </2 t3ss facilitatesevade host recognitionnlrp3 inflammasomes detectnlrp3 inflammasomes controlspi )- 1human naip detects1 t3sssalmonella </host cellthree ligandsinfected cells2 t3sss1 activation5 inflammasomessingle naipserovar typhimuriumreplicate intracellularlypathogenicity islandpartially requirednegative pathogenmurine naipsmediates caspaseintracellular survivalinner rodincluding naip1humans encodehuman naiphuman macrophagesfindings revealcombinatorial naipalso activated

Licence

CC BY 4.0

Exports