Steroidal Saponins from Fresh Stems of Dracaena angustifolia
journal contributionposted on 24.09.2010, 00:00 by Min Xu, Ying-Jun Zhang, Xing-Cong Li, Melissa R. Jacob, Chong-Ren Yang
Six new steroidal saponins (1−6), angudracanosides A−F, were isolated from fresh stems of Dracaena angustifolia, together with eight known compounds. The structures of compounds 1−6 were determined by detailed spectroscopic analyses and chemical methods. Antifungal testing of all compounds showed that 6 and 7 were active against Cryptococcus neoformans with IC50s of 9.5 and 20.0 μg/mL, respectively.