np100351p_si_001.pdf (1.22 MB)
Download file

Steroidal Saponins from Fresh Stems of Dracaena angustifolia

Download (1.22 MB)
journal contribution
posted on 24.09.2010, 00:00 by Min Xu, Ying-Jun Zhang, Xing-Cong Li, Melissa R. Jacob, Chong-Ren Yang
Six new steroidal saponins (16), angudracanosides A−F, were isolated from fresh stems of Dracaena angustifolia, together with eight known compounds. The structures of compounds 16 were determined by detailed spectroscopic analyses and chemical methods. Antifungal testing of all compounds showed that 6 and 7 were active against Cryptococcus neoformans with IC50s of 9.5 and 20.0 μg/mL, respectively.