Statistical analysis for the induction of unstable chromosome aberrations in metaphase chromosomes and G2-PCCs.
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posted on 2024-10-25, 17:22 authored by Tammy L. Smith, Terri L. Ryan, Maria B. Escalona, Igor E. Shuryak, Adayabalam S. BalajeeEstimated values for Var/Mean ±SE and U for dicentrics, centric rings, acentric rings, and fragments after various doses of x-rays in the blood samples of two donors are shown for colcemid arrested metaphase chromosomes and calyculin A induced G2-PCCs.
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using human centromeretelomere specific pnapeptide nucleic aciddose dependent increaseclear dose dependencybiodosimetry triage toolprematurely condensed chromosomeschromosome aberrations inducedfish staining techniqueabsorbed doses estimatedacentric ring chromosomespcc assay coupledfish based g2pcc assaydicentric chromosomesinduced g2acentric fragmentsradiation doseshigh dosesdifferent dosesxlink ">wide rangeturnaround timestatistically significantslightly highersitu hybridizationshortened versionscale radiologicalpotential implicationsobtain g2main goalgrossly likecytogenetic assessmentalso performed5 gy48 hrs4 gy36 hrs20 gy
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