Seven-Membered Cyclic Sulfite Eudesmane Derivatives: Partial Synthesis, Structural Determination, and Enzymatic Resolution
journal contributionposted on 2007-01-19, 00:00 authored by Andrés García-Granados, Andrés Parra, Francisco Rivas, Alejandro J. Segovia
Two chromatographically inseparable, diastereomeric eudesmane cyclic sulfites have been semisynthesized from α-santonin. This diastereomeric mixture was resolved by enzymatic acetylation with CCL. Each cyclic sulfite derivative was individually characterized on the basis of its spectroscopic and crystallographic properties.