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Seven-Membered Cyclic Sulfite Eudesmane Derivatives:  Partial Synthesis, Structural Determination, and Enzymatic Resolution

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journal contribution
posted on 2007-01-19, 00:00 authored by Andrés García-Granados, Andrés Parra, Francisco Rivas, Alejandro J. Segovia
Two chromatographically inseparable, diastereomeric eudesmane cyclic sulfites have been semisynthesized from α-santonin. This diastereomeric mixture was resolved by enzymatic acetylation with CCL. Each cyclic sulfite derivative was individually characterized on the basis of its spectroscopic and crystallographic properties.