pmed.1003732.s001.docx (34.33 kB)

STROBE Statement—Checklist of items that should be included in reports of cohort studies.

journal contribution

posted on 2021-08-31, 17:22 authored by Pradeep S. Chauhan, Kevin Chen, Ramandeep K. Babbra, Wenjia Feng, Nadja Pejovic, Armaan Nallicheri, Peter K. Harris, Katherine Dienstbach, Andrew Atkocius, Lenon Maguire, Faridi Qaium, Jeffrey J. Szymanski, Brian C. Baumann, Li Ding, Dengfeng Cao, Melissa A. Reimers, Eric H. Kim, Zachary L. Smith, Vivek K. Arora, Aadel A. Chaudhuri

STROBE, Strengthening the Reporting of Observational Studies in Epidemiology.

(DOCX)

History

Usage metrics

Read the peer-reviewed publication

Urine tumor DNA detection of minimal residual disease in muscle-invasive bladder cancer treated with curative-intent radical cystectomy: A cohort study

Categories

Keywords

study limitations included minimal residual disease cancer genome atlas residual disease detected utdna variant calling overall utdna level optimal utdna threshold median utdna level removing germline variants linear relationship derived highly significant accuracy 409 mibc tumors pathologic response based pathologic complete response whole exome sequencing define mrd detection dna damage response localized bladder cancer invasive bladder cancer utdna analysis revealed tumor mutational burden surgical sample (<received neoadjuvant chemotherapy intent radical cystectomy 4 – 38 15 healthy adults utdna mrd detection among mibc patients 5 mibc patients bladder cancer patients silent mutations detected noninvasively infer tmb pathologic response bladder cancer radical cystectomy neoadjuvant chemotherapy mutations detected healthy adults derived mutations detecting utdna silent mutation nucleotide variants noninvasively limits highly correlated free dna analysis restricted offer bladder generation sequencing deep sequencing xlink ">validation applied typically preceded tumor tissue targeted next similarly analyzed seq ),samples acquired november 2020 n </free survival confirmed diagnosis cohort yielded average age april 2019 86 ),85 %.69 years 007 ).002 ).

Licence

Exports