pone.0259556.s001.pdf (8.46 MB)
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journal contribution
posted on 2021-11-04, 17:27 authored by Melanie A. Sultana, Carmel Cluning, Wai-Sin Kwong, Nicole Polain, Nathan J. Pavlos, Thomas Ratajczak, John P. Walsh, Jiake Xu, Sarah L. Rea(PDF)
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transcription factor involvedpaget &# 8217nf -&# 954p62 regulates proteinsp62 regulate signallingscaffold protein sqstm1b signalling leadingunstressed cells cocells undergoing autophagyprotects ajuba levelshek293 cellsaltered levelsp62 reducesp62 observedp62 inhibitsxlink ">wild typevarious cancersthereby impactproteasome systemproteasomal stressprolonged ajubaosteoclast differentiationlysosome pathwayincreased levelshowever cofrequently mutateddependent mannercellular functionsb activityassociated domainajuba present
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