S1 File - Global burden of thyroid cancer in adolescents and young adults (aged 15–39 years) from 1990 to 2021: A systematic analysis of the Global Burden of Disease Study 2021

S1 Table. The Guidelines for Accurate and Transparent Health Assessment Reporting (GATHER). S2 Table. The Socio-demographic Index (SDI) reference values from the Global Burden of Disease (GBD) data released by the Institute for Health Metrics and Evaluation (IHME) in 2021. S3 Table. The Socio-demographic Index (SDI) values of 204 countries/territories from the Global Burden of Disease (GBD) data released by the Institute for Health Metrics and Evaluation (IHME) in 2021. S4 Table. The correspondence of Global Burden of Disease (GBD) regions with 204 countries/territories from the GBD data released by the Institute for Health Metrics and Evaluation (IHME) in 2021. S5 Table. Incidence of thyroid cancer in adolescents and young adults (AYAs), and their average annual percentage changes in 204 countries/territories from 1990 to 2021. S6 Table. Prevalence of thyroid cancer in adolescents and young adults (AYAs), and their average annual percentage changes in 204 countries/territories from 1990 to 2021. S7 Table. DALYs of thyroid cancer in adolescents and young adults (AYAs), and their average annual percentage changes in 204 countries/territories from 1990 to 2021. DALY = disability-adjusted life-year. S8 Table. The results of frontier analysis based on SDI and age-standardized DALYs rate for thyroid cancer in adolescents and young adults from 1990 to 2021. S9 Table. Incidence of thyroid cancer in adolescents and young adults (AYAs), and their average annual percentage changes from 1990 to 2021 by age at the global level. S10 Table. Prevalence of thyroid cancer in adolescents and young adults (AYAs), and their average annual percentage changes from 1990 to 2021 by age at the global level. S11 Table. DALYs of thyroid cancer in adolescents and young adults (AYAs), and their average annual percentage changes from 1990 to 2021 by age at the global level. DALY = disability-adjusted life-year. S12 Table. Decomposition of the percentage changes in thyroid cancer among adolescents and young adults (AYAs) worldwide from 1990 to 2021, alterations in incidence as influenced by aging, population growth, and epidemiological change. S13 Table. Decomposition of the percentage changes in thyroid cancer among adolescents and young adults (AYAs) worldwide from 1990 to 2021, alterations in prevalence as influenced by aging, population growth, and epidemiological change. S14 Table. Decomposition of the percentage changes in thyroid cancer among adolescents and young adults (AYAs) worldwide from 1990 to 2021, alterations in DALYs as influenced by aging, population growth, and epidemiological change. DALYs = disability-adjusted life-years. S15 Table. Prediction results of Bayesian age–period–cohort analysis (BAPC) in thyroid cancer among adolescents and young adults (AYAs) worldwide in 2040. S1 Fig. Cases and age-standardized rates of incidence at the regional level in 1990 and 2021. (A) Incidence cases; (B) Age-standardized incidence rates. S2 Fig. The APCs of ASR for thyroid cancer among adolescents and young adults (AYAs) at the global and regional level based on the Joinpoint regression analysis model. (A) Incidence cases; (B) Prevalence cases; (C) DALYs cases. DALYs = disability-adjusted life-years. S3 Fig. Cases and age-standardized rates of prevalence at the regional level in 1990 and 2021. (A) Prevalence cases; (B) Age-standardized prevalence rates. S4 Fig. Cases and age-standardized rates of DALYs at the regional level in 1990 and 2021. (A) Prevalence cases; (B) Age-standardized prevalence rates. DALYs = disability-adjusted life-years. S5 Fig. Numbers of incidence (thousand) for thyroid cancer among adolescents and young adults at global level in 2021. S6 Fig. Age-standardized rates for thyroid cancer in adolescents and young adults by SDI across 204 countries/territories in 2021. (A), Age-standardized incidence rates; (B), Age-standardized prevalence rates; (C), Age-standardized DALYs rates. SDI = Sociodemographic index. DALYs = disability-adjusted life-years. S7 Fig. Number of prevalence (thousand) for thyroid cancer among adolescents and young adults at global level in 2021. S8 Fig. Number of DALYs (thousand) for thyroid cancer among adolescents and young adults at global level in 2021. S9 Fig. Trends of incidence, prevalence and DALYs for thyroid cancer among adolescents and young adults from 1990 to 2021. (A) Trends in incident cases and age special incidence rate. (B) Trends in death cases and age special death rate. (C) Trends in DALYs cases and age special DALYs rate. DALYs = disability-adjusted life-years. S10 Fig. The results of Joinpoint regression analysis in five age groups at the global level from 1990 to 2021. (A) Incidence cases; (B) Prevalence cases; (C) DALYs cases. DALYs = disability-adjusted life-years. S11 Fig. The trends of numbers in incidence (A), prevalence (B), and DALYs (C) for thyroid cancer among adolescents and young adults by sex, from 1990 to 2021. DALYs = disability-adjusted life-years.

(PDF)