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Ruthenium-Catalyzed Pyrrole Synthesis via Oxidative Annulation of Enamides and Alkynes

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journal contribution
posted on 04.01.2013, 00:00 by Bin Li, Nuancheng Wang, Yujie Liang, Shansheng Xu, Baiquan Wang
An efficient and regioselective ruthenium-catalyzed oxidative annulation of enamides with alkynes via the cleavage of C(sp2)–H/N–H bonds is reported. The reactions can afford N-acetyl substituted or N-unsubstituted pyrroles by altering the reaction conditions slightly.

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