ol5b01979_si_001.pdf (10.12 MB)
Download fileRegioswitchable Palladium-Catalyzed Decarboxylative Coupling of 1,3-Dicarbonyl Compounds
journal contribution
posted on 2015-08-07, 00:00 authored by Miles Kenny, Jeppe Christensen, Simon
J. Coles, Vilius FranckevičiusA palladium-catalyzed
chemo- and regioselective coupling of 1,3-dicarbonyl
compounds via an allylic linker has been developed. This reaction,
which displays broad substrate scope, forms two C–C bonds and
installs two all-carbon quaternary centers. The regioselectivity of
the reaction can be predictably controlled by utilizing an enol carbonate
of one of the coupling partners.
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