ab8b01214_si_001.pdf (124.3 kB)
Rapid Coating Process Generates Omniphobic Dentures in Minutes to Reduce C. albicans Biofouling
journal contribution
posted on 2018-12-27, 18:42 authored by Anna Waterhouse, Daniel C. Leslie, Kayla Lightbown, Daniel Antonoff, Shanda Lightbown, Nikolaos Dimitrakakis, Julia B. Hicks-Berthet, Cheyene N. Leslie, Michael Super, Donald E. Ingber, Marc B. AckermanLocalized infections
caused by biofilm formation on dentures pose
a serious health risk for patients, especially the elderly, as they
can lead to complications such as pneumonia. Daily enzymatic denture
cleaners do not fully prevent biofilm formation on dentures. Here
we developed a rapid coating process to apply a liquid repellent surface
to dentures in ∼5 min and demonstrated a significant 225-fold
reduction of Candida albicans adhesion over 6 days,
compared to uncoated dentures. This rapid coating process could be
applied to dentures and other dental devices chair-side and allow
the research community to quickly and easily generate ominphobic surfaces.