Qualifying-Exam-Proposal.pdf (992.39 kB)
Qualifying Exam proposal: Drug repurposing on a heterogeneous network of pathogenesis
Here is my Qualifying Exam proposal, which I wrote as a second year PhD student in UCSF's Biological & Medical Informatics program. I proposed a technique for predicting new therapeutic applications of existing drugs using heterogeneous networks.
Note that after passing my Quals, I applied the proposed technique to a different problem: predicting disease–gene associations (https://doi.org/98q). However, starting in early 2015, I began the research proposed here as my final dissertation project. Readers interested in the actual project are encouraged to look at the updated proposal (https://doi.org/bd9g), which evolved considerably over the years.
I'd like to thank my advisor, Sergio Baranzini, who contributed greatly to the proposal by helping to conceive the project, introducing me to many of the concepts, and providing guidance and feedback on the drafts. I would also like to thank my Qualifying Exam committee, who also contributed much feedback. The committee consisted of Patsy Babbitt as Chair, Andrej Sali, Katie Pollard, and Jun Song.
My Qualifying Exam took place on June 24, 2013 but the committee requested some modifications to the proposal. Hence, this proposal is dated July 25, 2013.
