pgen.1010458.s013.pdf (1.4 MB)
Presence of the ARTenvV retroduplicated copy in O. dammah.
journal contribution
posted on 2022-10-14, 17:50 authored by J’Zaria Simpson, Christine A. Kozak, Guney BosoUpper panel shows the ARTenvV retroduplicated copy in the O. dammah genome with PCR primers indicated with arrows. The ARTenvV ORF is shown in yellow and the Refseq annotated gene in green. Lower panel shows the PCR products of the indicated species. The gel is representative of two independent experiments.
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transcriptomic analyses showsubsequent mammalian diversificationtwo mammalian ordersmammalian orders artiodactylaenv proteins lackdiv >< pancient endogenous retroviruserv gene derivedrespective ordersenvelope geneenv endogenous retrovirusesancient retrovirusesorthologous ervoriginal retroviruslike retrovirusancestral retrovirusvertebrate genomesunique opportunitytransmembrane motifsurface orfstudy viralspecies transmissionsspecies transmissionroughly coincidesretroviral invasionspositive selectionordinal transmissionmutated remainsmultiple linesindependently endogenizedhost interactionshost functionfirst discoveryfindings identifyevidence indicateerv genesdeep timecarenvv artenvv ancestral species