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Polymer Microarrays for the Discovery and Optimization of Robust Optical-Fiber-Based pH Sensors

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journal contribution
posted on 11.04.2019, 00:00 authored by Jingjing Gong, Seshasailam Venkateswaran, Michael G. Tanner, James M. Stone, Mark Bradley
Polymer microarrays were utilized for the high-throughput screening and discovery of optimal polymeric substrates capable of trapping functional ratiometric fluorescence-based pH sensors. This led to the identification of poly­(methyl methacrylate-co-2-(dimethylamino) ethyl acrylate) (PA101), which allowed, via dip coating, the attachment of fluorescent pH sensors onto the tips of optical fibers, resulting in robust, rapid, and reproducible sensing of physiological pHs.

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