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Plots of T′ for the log(posterior density) and number of non-ancestral recombinations for all 450 data sets.

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posted on 2022-03-09, 18:41 authored by Ali Mahmoudi, Jere Koskela, Jerome Kelleher, Yao-ban Chan, David Balding

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Bayesian inference of ancestral recombination graphs
PLOS Computational BiologyPLOS Computational Biology

Categories

  • Genetics
  • Molecular Biology
  • Evolutionary Biology
  • Biological Sciences not elsewhere classified
  • Mathematical Sciences not elsewhere classified
  • Cancer
  • Infectious Diseases

Keywords

unlike previous methodsproviding interpretable assessmentsallowed great advanceskey evolutionary parametersshow using simulationsdiv >< pancestral recombination graphyet probabilistic inferenceprobabilistic inferenceevolutionary historybayesian inferenceaccurate inferencewell calibratedseveral hundredssequence siterecombination eventspoint estimationnovel algorithmgenealogical treedna sequencescurrently limitedcomputational improvementsbranch lengthsarginfer </

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