Photocatalytic <i>N</i>‑Alkylation of <i>N</i>H‑Diaryl Sulfondiimines via Anti-Markovnikov Hydroamination with Styrenes

Sulfondiimines, which are isoelectronic with sulfones and sulfoximines, represent a neglected yet intriguing pharmacophore in the discovery program. Herein, we present a facile and mild photocatalytic anti-Markovnikov hydroamination of styrenes for the construction of <i>N</i>-alkylated sulfondiimines with primary, secondary, and tertiary alkyl substituents. A sulfondiimine-derived analogue of the marketed drug Vioxx was synthesized using this method as the key step.