ol501070g_si_001.pdf (6.46 MB)
Download file

Palladium-Catalyzed C(sp2)–H Pyridocarbonylation of N‑Aryl-2-aminopyridines: Dual Function of the Pyridyl Moiety

Download (6.46 MB)
journal contribution
posted on 16.05.2014, 00:00 by Dongdong Liang, Yimiao He, Qiang Zhu
An efficient synthesis of 11H-pyrido­[2,1-b]­quinazolin-11-one through palladium-catalyzed C­(sp2)–H pyridocarbonylation of N-aryl-2-amino­pyridines has been developed. The pyridyl group acts as an intramolecular nucleophile for the first time in C–H carbonylation reactions.

History