ja7b04312_si_001.pdf (11.2 MB)
Nickel-Catalyzed C‑Alkylation of Nitroalkanes with Unactivated Alkyl Iodides
journal contributionposted on 2017-06-08, 16:48 authored by Sina Rezazadeh, Vijayarajan Devannah, Donald A. Watson
Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary, and tertiary alkyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to diverse nitroalkanes.