Naturally occurring paraherquamides and their analogues (Fungal source, host, place, molecular weights, and formulae).
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posted on 2024-11-07, 18:41 authored by Anfal S. Aljahdali, Abdelsattar M. Omar, Gamal A. Mohamed, Ali M. Almalki, Sabrin R. M. IbrahimNaturally occurring paraherquamides and their analogues (Fungal source, host, place, molecular weights, and formulae).
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silico adme assessmentshowed comparable dockingparasites develop resistanceparaherquamides &# 8211molecular dynamics simulationsincluding molecular dockingfavorable pharmacokinetic propertiesevade host defensescomputational analysis setunique structural featuresdeveloping new therapeuticsdiv >< pnematode infections impose48 paraherquamide analogspotential anthelmintic agentsanthelmintic agentsnematode infectionsstructural differencesparaherquamide knew hopenematode neurotransmissionvivo study highlightstudy exploressignificant healthpromising resultspolycyclic spirooxygenated 7oxindole alkaloidsnative antagonistmembered ringinsights gainedgreat expectationsexisting treatmentseconomic burdenclinical studiesanalogs studiedachbp receptor
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