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Mutation, Replication, and Evolution: How Viruses Adapt and Survive

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posted on 2025-02-02, 19:20 authored by Sumaia Alam RaishaSumaia Alam Raisha

Viruses are microscopic infectious agents that rely on host cells to replicate and mutate. Their high mutation rates, particularly in RNA viruses, impact their transmissibility, virulence, and ability to evade immune responses. Various factors influence viral mutations, including replication mechanisms, genome size, and host interactions. While some mutations can reduce a virus’s ability to cause disease, others complicate treatment and vaccine development. Understanding viral mutation rates and replication models, such as the "stamping machine" and semi-conservative replication, is crucial for predicting future outbreaks and improving public health responses.

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Viral mutations, driven by replication mechanisms, genome size, and host interactions, impact vaccine effectiveness and disease evolution. RNA viruses mutate rapidly, requiring frequent vaccine updates, while smaller genomes evolve faster. Understanding these factors is key to predicting outbreaks and improving treatments.

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