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Multiple sequence alignment of Aurora Kinase (AUK) orthologous from the indicated species.

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posted on 2021-07-14, 17:40 authored by Edio Maldonado, Diego A. Rojas, Fabiola Urbina, Aldo Solari

Sequences were aligned using the Clustal Omega tool (https://www.ebi.ac.uk/Tools/msa/clustalo/). The active site and the activation loop of the enzyme from those species is indicated.

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T. cruzi DNA polymerase beta (Tcpolβ) is phosphorylated in vitro by CK1, CK2 and TcAUK1 leading to the potentiation of its DNA synthesis activity
PLOS Neglected Tropical DiseasesPLOS Neglected Tropical Diseases

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Tcpol βDNA polymerase βphosphorylate Tcpol β. CK 2TcAUK 1casein kinase 1BERprotein kinasesconsensus phosphorylation sitescruzi DNA polymerase betaphosphorylate Tcpol β. Pharmacologi...Genes encoding orthologuesDNA polymerase activityDNA synthesis activityDNA base excision repair

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