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MOESM2 of Skin collagen fluorophore LW-1 versus skin fluorescence as markers for the long-term progression of subclinical macrovascular disease in type 1 diabetes

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posted on 2016-02-11, 05:00 authored by David Sell, Wanjie Sun, Xiaoyu Gao, Christopher Strauch, John Lachin, Patricia Cleary, Saul Genuth, Vincent Monnier
Additional file 2. Levey-Jennings plot for LW-1 assay in the DCCT study. The plot consists of injection number on the x-axis (i.e., from 1 to 357 in consecutive order over the six week course of the HPLC assay) vs. integrated peak areas on the y-axis (relative fluorescence at ex/em 348/463 nm) for all samples injected (n = 216 DCCT + n = 42 nondiabetic controls + n = 13 repeats), LQC (n = 13), HQC (n = 14), LW-1 QC standard (n = 49) and enzyme blanks (n = 10).


National Institute of Diabetes and Digestive and Kidney Diseases