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MOESM12 of Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy

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journal contribution
posted on 13.12.2019, 07:39 by Cynthia Shu, Ariana Kaxon-Rupp, Judd Collado, Robert Damoiseaux, Rachelle Crosbie
Additional file 12: Figure S7. Titration of screen hits on hSSPN-EGFP myotubes. hSSPN-EGFP myotubes were treated with 1 nM-20 μM of (a) felodipine of (b) nilvadipine for 48 h and imaged at day 4 of differentiation using a high-content imager (n = 12). Images were analyzed using a MetaXpress custom module to calculate fluorescence over vehicle (R.U., relative units).


National Institute of Arthritis and Musculoskeletal and Skin Diseases