ol015547c_si_002.pdf (34.17 kB)
Iodine Monochloride/Silver Trifluoromethanesulfonate (ICl/AgOTf) as a Convenient Promoter System for O-Glycoside Synthesis
journal contributionposted on 2001-02-17, 00:00 authored by Teddy Ercegovic, Andreas Meijer, Göran Magnusson, Ulf Ellervik
The novel promoter system iodine monochloride/silver trifluoromethanesulfonate (ICl/AgOTf) was evaluated with various thioglycoside donors and saccharide acceptors, and O-glycosides were obtained in 46−82% yield. Several practical advantages of the ICl/AgOTf system over known promoter systems were observed, such as convenient handling of the reagents and absence of byproducts related to N-succinimide.