Funnel plot, adjusted with the trim-and-fill method.
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posted on 2025-05-05, 17:38 authored by Henning Budde, Nina Dolz, Anett Mueller-Alcazar, Fabian Schacht, Bruna Velasques, Pedro Ribeiro, Sergio Machado, Mirko WegnerThis figure shows the adjusted analysis of publication bias.
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total sample consistingreducing depressive symptomspooled results indicatenew findings sinceexact mechanisms underlying229 individual studies10 years updatemoderate clinical effecteffect sizes calculationsystematic literature searchotherwise healthy adultsfrequently implemented interventionci [− 0consistently positive effectsalternative treatment methodsxlink "> depressionxlink ">positive effectsystematic reviewhelpful alternativeappropriate literaturewaiting listurgently indicatedside effectsphysical activityneurological changesneurobiological explanationsmethodological characteristicsmajor burdeninclusion criteriaincluded searchingconventional therapiescontrol groupscinahl completecheck whetherart reviewantidepressant effectsamstar 2also associatedactivity placebo43 ],255 participants
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