rspb20200798_si_001.pdf (117.84 kB)
Download file

Figures S1 and S2; Tables S1 and S2 from Loss of hypoxia-inducible factor 1α affects hypoxia tolerance in larval and adult zebrafish (Danio rerio)

Download (117.84 kB)
journal contribution
posted on 11.05.2020, 07:24 by Milica Mandic, Carol Best, Steve F. Perry
Figure S1. O2 consumption (ṀO2) across a range of water PO2 in wild-type (A), Hif1aa-/- (B), Hif1ab-/- (C) and Hif1aa-/-ab-/- (D) 7 day post fertilization (dpf) larvae reared in normoxia, 12 kPa hypoxia from 4 to 7 dpf and 4 kPa hypoxia from 6 to 7 dpf.;Figure S2. O2 consumption (ṀO2) across a range of water PO2 in wild-type (A), Hif1aa-/- (B), Hif1ab-/- (C) and Hif1aa-/-ab-/- (D) adult zebrafish. ;Table S1. Comparison of critical O2 tension (Pcrit) calculated using broken stick regression (BSR) and as a linear function of ṀO2 measured at low PO2 (LLO) in wild- type, Hif1aa-/-, Hif1ab-/- and Hif1aa-/-ab-/- in 7 days post fertilization larval zebrafish reared under three different O2 conditions: normoxia, 12 kPa and 4 kPa.;Table S2. Comparison of critical O2 tension (Pcrit) calculated using broken stick regression (BSR) and as a linear function of ṀO2 measured at low PO2 (LLO) in wild-type, Hif1aa-/-, Hif1ab-/- and Hif1aa-/-ab-/- in adult zebrafish.

History