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Facile Synthesis of Highly Functionalized N-Methyl Amino Acid Esters without Side-Chain Protection

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journal contribution
posted on 15.09.2005, 00:00 authored by Kimberly N. White, Joseph P. Konopelski
The facile, two-pot synthesis of N-methyl amino acid esters by way of reductive amination is presented. Side chain protection schemes are not required, the starting materials are all commercially available, and the synthetic method is straightforward and affords desired product in very high yield.

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