Enumeration of DAPI+CK+CD45- or DAPI+panCK+CD45- cells detected in healthy bone marrow samples processed with GEM devices functionalized with either anti-EpCAM or anti-EGFR antibodies.
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posted on 2025-03-12, 17:35 authored by Minh-Chau N. Le, Dongjiang Chen, Kierstin A. Smith, David D. Tran, Z. Hugh FanEnumeration of DAPI+CK+CD45- or DAPI+panCK+CD45- cells detected in healthy bone marrow samples processed with GEM devices functionalized with either anti-EpCAM or anti-EGFR antibodies.
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two timepoints revealedreleasing captured cellsminimal residual diseasemaintaining high viabilityenhancing dtc detectiondistant organs includingbreast cancer prognosisbreast cancer patientpotential dynamic interplaybreast cancerstudy introducedstandard approachshed lightresults underscoreoptimizing immunocaptureobservation suggestedmajor causefold enrichmentenrichment methodsbone marrowbased approachaggressive nature
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