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Electrochemical Method for the Synthesis of Disulfides of 2‑(Benzo[d]thiazol(or oxazol)-2-ylamino)-5-morpholinobenzenethiol

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journal contribution
posted on 2013-05-17, 00:00 authored by Roya Esmaili, Davood Nematollahi
Electrochemical synthesis of two new disulfides of 2-(benzo­[d]­thiazol­(or oxazol)-2-ylamino)-5-morpholinobenzene thiols was carried out via the electrooxidation of 4-morpholinoaniline in the presence of 2-mercaptobenzothiazole and 2-mercaptobenzoxazole. Our results indicate that electrogenerated p-quinonediimine participated in a Michael-type addition reaction with 2-SH-benzazoles and after intramolecular nucleophilic substitution reaction and electrooxidative disulfide bond formation were converted to the corresponding disulfide compounds.