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Effect of YAP on the expression of inflammatory genes.

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journal contribution
posted on 02.12.2020, 18:47 authored by Masum M. Mia, Dasan Mary Cibi, Siti Aishah Binte Abdul Ghani, Weihua Song, Nicole Tee, Sujoy Ghosh, Junhao Mao, Eric N. Olson, Manvendra K. Singh

Two luciferase reporters (NF-kB-Luc and IL6-Luc) were used with YAP in the presence or absence of Hippo signaling inhibitor verteporfin (VP) or MAPK inhibitor SB203580. (A) Results of normalized luciferase reporter assays in HEK293T cells with NF-кB-luciferase reporter in the presence of YAP. (B) IL6-luciferase reporters were transfected in HEK293T cells with or without YAP in the presence or absence of VP or SB203580. All the experiments repeated at least 3 times. For numerical raw data, please see S1 Data.