ECO FRIENDLY ROUTE OF DEHYDROGENATION OF 2,3-DIHYDRO-2-PHENYL-4-QUINOLONE TO 2-PHENYL-4-QUINOLONE USING DIACETOXY IODO BENZENE

As an alternative reagent to various traditional dehydrogenating reagents Diacetoxy iodo benzene is stable, non-hazardous, acidic and has been successfully used 1for dehydrogenation reactions . Herein we report a new and ecofriendly route for dehydrogenation of 2,3-dihydro-2- phenyl-4-quinolone to 2-phenyl-4-quinolone using diacetoxy iodo benzene and 2potassium hydroxide . A series of 2,3-dihydro-2-phenyl-4-quinolones3 has been synthesized using acid-catalyzed one-pot reaction quinolones were prepared through cyclization of the condensation product that were formed by heating of arylamines and ethyl benzoylacetate in toluene. Similarly, the 6 (7 or 8)-substituted 2,3-dihydro-2- phenylquinolones were prepared from the para (ortho or meta)-substituted aniline.