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Diverse Mechanistic Pathways and Selectivities in Organo-f-Element-Catalyzed Hydroamination. Intermolecular Organolanthanide-Catalyzed Alkyne and Alkene Hydroamination

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journal contribution
posted on 1996-09-03, 00:00 authored by Yanwu Li, Tobin J. Marks
Lanthanide metallocenes catalyze the regiospecific intermolecular addition of primary amines to acetylenic, olefinic, and diene substrates at rates which are ∼1/1000 those of the most rapid intramolecular analogues. Kinetic and mechanistic data argue for turnover-limiting C⋮C/CC insertion into a Ln−N bond, followed by protonolysis of the resulting Ln−C bond.