Direct analysis of oil additives by high-field asymmetric waveform ion mobility spectrometry-mass spectrometry combined with electrospray ionization and desorption electrospray ionization
journal contributionposted on 15.03.2016, 13:41 by Caitlyn Da Costa, Matthew TurnerMatthew Turner, Jim ReynoldsJim Reynolds, Samuel Whitmarsh, Tom Lynch, Colin Creaser
© 2016 American Chemical Society. The analysis of corrosion inhibitors in the presence and absence of an oil matrix is reported using electrospray ionization (ESI) and desorption electrospray ionization (DESI), hyphenated with miniaturized high-field asymmetric waveform ion mobility spectrometry (FAIMS) and mass spectrometry (MS). The target analytes were successfully ionized in solution by ESI and directly from steel surfaces using DESI ambient ionization at levels ≥0.0004% w/w (4 ppm) in oil. Differences in the mass spectral profiles observed for the additive/oil mixture are attributed to differences between the ESI and DESI ionization processes. The use of FAIMS improved selectivity for ESI generated analyte ions through reduction in the chemical noise resulting from the oil matrix. DESI enabled the direct, rapid, native state interrogation of oil samples on steel surfaces without sample pretreatment, and the hyphenation of DESI with the miniaturized FAIMS enhanced the relative analyte responses of the surface-active corrosion inhibitors.
The authors would like to thank the Engineering and Physical Sciences Research Council and BP for an Industrial CASE Studentship