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Detecting cord blood cell type-specific epigenetic associations with gestational diabetes mellitus and early childhood growth

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journal contribution
posted on 2021-06-17, 15:03 authored by Tianyuan LuTianyuan Lu
Full summary statistics for cell type-specific epigenome-wide association studies

Open Access article now available at https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-021-01114-5

ewas_cellspecific_GDM.RData: DNA methylation associated with gestational diabetes mellitus, based on M-values
ewas_cellspecific_GDM_bval.RData: DNA methylation associated with gestational diabetes mellitus, based on beta-values
ewas_cellspecific_3yobmi.RData: DNA methylation associated with age 3 BMI z-score, based on M-values
ewas_cellspecific_3yobmi_bval.RData: DNA methylation associated with age 3 BMI z-score, based on beta-values

Standard outputs generated by CellDMC function implemented in the EpiDISH R package
Each *celldmc* object contains a "dmct" data frame indicating cell type-specific differential methylation and a "coe" data frame detailing estimated coefficients

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    Keywords

    EWAS analysisDNA methylation analysescell type specificitygestational diabetes mellitus (GDM)early childhood developmentEpigenetics (incl. Genome Methylation and Epigenomics)

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    CC BY 4.0

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