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Copper-Catalyzed Intermolecular Carboamination of Alkenes Induced by Visible Light

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journal contribution
posted on 25.02.2019, 16:43 by Yang Xiong, Xiaodong Ma, Guozhu Zhang
A photoinduced copper-catalyzed three-component reaction involving carbohalide, alkene and amine has been developed, leading to valuable fluoroalkyl-containing amines. A sole inexpensive CuCl is used as the photo- and coupling catalyst. A broad array of substrates are capable coupling partners. The diverse method is compatible with a broad range of functional groups and can be further applied to the late-stage functionalization of bioactive pharmaceuticals.

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