ol9b00252_si_001.pdf (6.92 MB)
Download file

Copper-Catalyzed Intermolecular Carboamination of Alkenes Induced by Visible Light

Download (6.92 MB)
journal contribution
posted on 25.02.2019, 16:43 by Yang Xiong, Xiaodong Ma, Guozhu Zhang
A photoinduced copper-catalyzed three-component reaction involving carbohalide, alkene and amine has been developed, leading to valuable fluoroalkyl-containing amines. A sole inexpensive CuCl is used as the photo- and coupling catalyst. A broad array of substrates are capable coupling partners. The diverse method is compatible with a broad range of functional groups and can be further applied to the late-stage functionalization of bioactive pharmaceuticals.