Comparison of the final apo model to the AlphaFold2 model.
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posted on 2025-01-09, 18:49 authored by Ranjit K. Deka, Shih-Chia Tso, Wei Z. Liu, Chad A. BrautigamThe AlphaFold2 model is shown in gray, and the Apo-TV0924 in varied colors (see Fig 4A in the main text).
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related treponemal speciesmicroaerophilic host environmentscycle enzymes suggestedalternative sources couldevidence strongly supportedtreponema vincentii biochemical evidence supportssecond crystal structurenamed tp0476 ),div >< pacid sequence identityknown acetate kinasesalternative energy sourcetreponema pallidum 3 å resolutionbiochemical evidencecrystal structureenergy sourceacetate kinasespallidum 36 åacetogenic energyacetate kinasesole carbonsimilar foldrecent bioinformaticprovided insightparasitic spirocheteostensibly catalyzesoral pathogenkey componenthuman diseasehomologous enzymefinal enzymeenzyme ’enzyme existsenzymatic activity
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