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Chemical constituents of Viscum coloratum (Kom.) Nakai and their cytotoxic activities

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journal contribution
posted on 2020-10-27, 09:50 authored by Ying-Ying Chen, Jiang-Ping Hou, Ling Huang, Afsar Khan, Fei-Fei Xing, Xiao-Han Zhang, De-Feng Han, Shi-Li Yan, Gui-Dong Cao, Qi-Yang Jiao, Dejie Liu, Xuwei Zhu, Qingwen Hu, Hong-Xiang Lou

A new diarylheptanoid, (1 R,2S,3S,5S)-2,3-dihydroxy-3',3''-dimethoxy-4'-de-O-methylcentrolobine (1) and a new bisabolane-type sesquiterpenoid, (1 R,7S)-1,12,13-trihydroxybisabola-3,10-diene (2), together with nineteen known compounds (3-21) were isolated from the EtOH extract of the stems and branches of Viscum coloratum (Kom.) Nakai. Their structures were elucidated by extensive analysis of 1 D and 2 D NMR spectra and from the HRESIMS. All the compounds were evaluated for their cytotoxic activity against eight human tumor cell lines.

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