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Asymmetric Synthesis of Four Isomers of 2-C-Trifluoromethylerythritol

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journal contribution
posted on 2006-04-14, 00:00 authored by Hua Wang, Xiaoming Zhao, Youhua Li, Long Lu
Optically active 2-C-trifluoromethylerythritols, analogues of 2-C-methylerythritol, which is a key intermediate in the biosynthesis of isoprenoid with a mevalonate-independent route, were conveniently synthesized from 1,1,1-trifluoro-2,3-epoxypropane.