An example from 42 one-way switch GRNs having no essential edge obtained by ESr.
journal contribution
posted on 2024-11-18, 18:26 authored by Macoto KikuchiThe red lines with arrowhead indicate activation and the blue lines with barhead indicate repression.
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three response typesrandomly generated setgene regulatory networksdifferent network structuresphenotype selection dueusing numerical simulationsthree distinguishable phenotypesrobust grns obtainedcommon core motifway switch grnsrobust grns lackrobust grnsgrns usingway switchevolutionary simulationsdifferent phenotypesway switchestoggle switchselection mechanismselection biasxlink ">target proteinstatistical physicsrealized cooperativelymuch highermany geneshardly selectedenvironmental conditionscooperative genotypes
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